NIAID Functional Genomics

The Functional Genomics Program for understanding the functions of uncharacterized genes in infectious disease pathogens will generate experimental data to determine the biochemical function(s) of hypothetical genes, unknown open reading frames, and non-coding RNAs. The program will apply state-of-the-art technologies to determine the biochemical and physiological roles of these gene components. Obtaining a more comprehensive understanding of uncharacterized genes in infectious disease pathogens will lead to improved genomic annotation and allow for the development of potential new targets for medical diagnostics, therapeutics and vaccines. The program will distribute data, software, and reagents generated from the research projects to the broader scientific community.

For more information on the three bacterial functional genomics projects and integration of the data into the PATRIC resource, please visit:

Functionalizing Lists of Unknown TB Entities (FLUTE)

Chicago Center for Functional Annotation (CCFA)

Genes Unknown in Acinetobacter baumannii (GUNK)