Comparative Genomic Analysis at PATRIC, A Bioinformatic Resource Center. Book chapter in Host Bacterial Infections, Methods in Molecular Microbiology.

Wattam, A., J. Gabbard, M. Shukla, and B. Sobral. (2014). Comparative Genomics Analysis at the PATRIC, A Bioinformatic Resource Center. In A. Vergunst and D. O’Callaghan (Eds.), Host Bacterial Infections, Methods in Molecular Microbiology (v. 1197, pp. 287-308).  Springer New York. doi: 10.1007/978-1-4939-1261-2_17. PMID: 25172288.

 

Abstract

The Pathosystems Resource Integration Center (PATRIC) is a genomics-centric relational database and bioinformatics resource designed to assist scientists in infectious-disease research. This method paper provides detailed instructions on using this resource to finding data specific to genomes, saving it in a personalized workspace and using a variety of interactive tools to analyze that data. While PATRIC contains many diverse tools and functionalities to explore both genome-scale and gene expression data, the main focus of this chapter is on comparative analysis of bacterial genomes.