Tim Driscoll, Joseph L. Gabbard, Chunhong Mao, Oral Dalay, Maulik Shukla, Clark C. Freifeld, Anne Gatewood Hoen, John S. Brownstein JS, Bruno W. Sobral. Integration and visualization of host-pathogen data related to infectious diseases. Bioinformatics. 2011 Jun 27. [Epub ahead of print] PubMed PMID: 21712250.
Infectious disease research is generating an increasing amount of disparate data on pathogenic systems. There is a growing need for resources that effectively integrate, analyze, deliver and visualize these data, both to improve our understanding of infectious diseases and to facilitate the development of strategies for disease control and prevention.
We have developed Disease View, an online hostpathogen resource that enables infectious disease-centric access, analysis, and visualization of host-pathogen interactions. In this resource, we associate infectious diseases with corresponding pathogens, provide information on pathogens, pathogen virulence genes and the genetic and chemical evidences for the human genes that are associated with the diseases. We also deliver the relationships between pathogens, genes, and diseases in an interactive graph and provide the geolocation reports of associated diseases around the globe in real time. Unlike many other resources, we have applied an iterative, user-centered design process to the entire resource development, including data acquisition, analysis, and visualization. Availability and Implementation: Freely available at http://www.patricbrc.org; all major web browsers supported.
View Full Paper at PubMed